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. 2014 Apr 16;8(1):211–217. doi: 10.3892/ol.2014.2071

Figure 5.

Figure 5

In vitro cell invasion in melanoma cells with overexpression and knockdown of angiopoietin-like 4 (ANGPTL4) and/or aldolase A (ALDOA) WM-115 cells: In vitro cell invasion assays were performed in control cells, cells stably transfected with empty pcDNA3 vector, cells overexpressing ANGPTL4, cells stably expressing ALDOA-shRNA, and cells overexpressing ANGPTL4 plus stably expressing ALDOA-shRNA. WM-266-4 cells: In vitro cell invasion assays were performed in control cells, cells stably transduced with scramble control shRNA, cells stably expressing ANGPTL4-shRNA, cells overexpressing ALDOA, and cells stably expressing ANGPTL4-shRNA plus overexpressing ALDOA. Invaded cell numbers were counted. WM-115 cells: αP<0.05, compared with Control and Vector; βP<0.05, compared with ANGPTL4; γP<0.05, compared with ALDOA-shRNA. WM-266-4 cells: δP<0.05, compared with Control and Scramble; χP<0.05, compared with ANGPTL4-shRNA.