Table 1.
Coagulation Parameters: | Patient 1 | Patient 2 | Normal values |
---|---|---|---|
Prothrombin time (PT) | 0.94 | 0.93 | 0.7–1 |
Activated partial thromboplastin time (PTT), sec | 20–32 | ||
Prothrombin time international normalized ratio (INR) | 1 | 1.02 | <1.2 |
Fibrinogen (mg/dL) | 242 | 286 | 200–400 |
Serum cross-linked fibrin (XDP) | 233 | N.A. | <0.20 |
Inherited prothrombotic disorders: | |||
Protein C, % | 100 | 104 | 70–140 |
Protein S, % | 56 | 68 | 53–100 |
AT Mutation, % | 87 | 75 | 70–120 |
Factor V Leiden Mutation (R506Q) | Absent | Absent | Absent |
Factor II Mutation (G20210A) | Absent | Absent | Absent |
MTHFR (Homocysteine) Mutation | Absent | Absent | Absent |
Acquired prothrombotic disorders: | |||
Jak 2 (Val617Phe) | Absent | Absent | Absent |
Anticardiolipin Ab | Absent | Absent | Absent |
LA1 (DRV) (sec) | 0.8 | 39.5 | <45 |
N.A. Not available.