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Tumorigenicity experiments with the SFCs derived from the SKOV3 cell line and the parental cells in BALB/c-nu mice.
| Cell type | Cell numbers | Incidence, n | Latency, days |
|---|---|---|---|
| Parental cells | 5×104 | 0/4 | - |
| 1×105 | 0/4 | - | |
| 2×105 | 3/4 | 35 | |
| 5×105 | 4/4 | 29 | |
| 1×106 | 4/4 | 12 | |
| CD133+ cells | 5×102 | 0/4 | - |
| 1×103 | 4/4 | 25 | |
| 5×103 | 4/4 | 13 | |
| 1×104 | 4/4 | 9 | |
| 5×104 | 4/4 | 6 |
SFCs, sphere-forming cells; CD, cluster of differentiation.
