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. 2014 Apr 25;8(1):266–274. doi: 10.3892/ol.2014.2095

Figure 2.

Figure 2

(A) Matrigel invasion assays of parental U373MG and D54MG cells cultured in normoxia or hypoxia. Data are presented as the mean ± SEM (n=6) *P<0.05 and **P<0.01, vs. the corresponding cells in normoxia. (B) Invasion assays of the same cells in hypoxia, with or without 50 μM chloroquine or 2 μM MMP inhibitor GM6001 for 24 h. Data are presented as the percentage of hypoxia-induced invasion (mean ± SD, n=3) **P<0.01 and ***P<0.001, vs. the corresponding vehicle treatments. MMP, matrix metalloproteinase.