Table I.

Basal mRNA expression in the TLR9 siRNA cells relative to the corresponding control siRNA cells in normoxia.

mRNA	D54MG TLR9 siRNA	U373MG TLR9 siRNA
TLR9	0.34±0.03c	0.63±0.08c
MMP-2	1.24±0.09b	1.19±0.09a
MMP-9	0.99±0.12d	1.27±0.14b
MMP-13	1.31±0.11b	1.09±0.10d
TIMP-3	1.47±0.101c	1.26±0.04c

^aP<0.05,

^bP<0.01 and

^cP<0.001;

^dP>0.05.

TLR9, Toll-like receptor-9; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinases.