Table 1. Parameters of the computational model.

Parameter	Description	Dimension	Value	Reference
	Half-saturation constant1			[50]
	Maximum rate constant 1 and 2			[50]
	Initial number of active sites 1,2 and 3			[50], [45]
	Half-saturation constant 2			[50]
	Half-saturation constant 3			[45]
	Maximum rate constant 3			[45]
	Cell volume			Our data
	Cell diameter			Our data
	Cell surface			Our data
	Diffusion coefficient of silicic acid in water			[41]

The values for the range of parameters for the optimization search are approximate values, based on experimental measurements.