Table 1.
Baseline characteristics of participants and dropouts at T0 (n = 49)
| Participants (n = 35) | Dropouts (n = 14) | p-value | |
|---|---|---|---|
| Age at diagnosis |
39 ± 13 |
36 ± 13 |
0.53 |
| Sex (males) |
33 (94%) |
14 (100%) |
1.0 |
| FVC% predicted |
102 ± 17 |
97 ± 13 |
0.37 |
| FEV1% predicted |
91 ± 16 |
90 ± 16 |
0.89 |
| FEV1/FVC |
75 ± 9 |
74 ± 10 |
0.50 |
| PD20 (mg) |
0.95 (1.7) |
0.30 (0.5) |
0.03 |
| NSBHR positivity |
23 (68%) |
11 (92%) |
0.13 |
| Total exposure time (months) |
51 (104) |
74 (89) |
0.77 |
| Time with symptoms (months) |
12 (26) |
24 (31) |
0.38 |
| Smokers |
10 (29%) |
6 (43%) |
0.5 |
| Pack-years* |
25 (24) |
13 (14) |
0.16 |
| Upper airway symptoms |
28 (80%) |
11 (79) |
1.0 |
| Asthma symptoms |
34 (97%) |
14 (100) |
1.0 |
| Asthma medication | 31 (91%) | 8 (89) | 1.0 |
Legend: FVC = forced expiratory vital capacity. FEV1 = forced expiratory volume in 1 second. NSBHR = nonspecific bronchial hyperreactivity. PD20 = provocative dose of methacholine producing a fall in FEV1 of 20%. *Pack-years for smokers and ex-smokers added. Data is presented as mean ± SD, median and interquartile range (IQR) or number (%).