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. 2014 Mar 18;20(4):542–559. doi: 10.1093/humupd/dmu008

Table I.

Levels of androgens in maternal serum.

Androgen Non-pregnant First trimester Second trimester Third trimester References
fT (pmol/l) 6.2 11.1 7.5 13.3 Wilke and Utley (1987)
tT (mmol/l) 0.21–2.98 0.90–7.32 1.20–8.40 2.20–10.70 O'Leary et al. (1991)
A4 (ng/ml) 1.0–2.0 2.5–3.5 0.6–7.8 1.6–14.0 Castracane et al. (1998), Carlsen et al. (2006)
DHT (ng/ml) 0.022–0.107 0.113 0.18 0.1–0.3 Buster et al. (1979), Dawood and Saxena (1977)
SHBG (nmol/l) 42.2 68.1 279.3 246.1 Wilke and Utley (1987)
DHEA (nmol/l) 1.0–40.0 10.0–60.0 5.0–50.0 5.0–50.1 Tagawa et al. (2004)
DHEAS (nmol/l) 2000–4000 2000–4000 500–2000 500–200 Tagawa et al. (2004)

The table shows the mean concentrations of androgens as given in references quoted. tT, total testosterone; fT, free testosterone; SHBG, sex hormone binding globulin; DHEA, dehydroepiandrosterone; DHEAS, dehydroepiandrosterone sulphate; A4, androstenedione; DHT, dihydrotestosterone.