Table 5. Alignments of the epitope sequences among H5N1 strains.
| Interacting antibody | OM-b/AY-2C2 epitope* | YH-1A1 epitope* | |||||
| Amino acid sequence (H5 numbering) | 43 | 45 | 46 | 139 | 140 | ||
| A/Vietnam/1194/2004 (1) | D | D | G | G | K | ||
| A/Vietnam/1203/2004 (1) | D | D | G | G | K | ||
| Human | A/Indonesia/05/2005 (2.1.3.2) | D | D | G | G | S | |
| strain | A/Turkey/12/2006 (2.2) | D | D | G | G | R | |
| (clade) | A/Anhui/01/2005 (2.3.4) | D | D | G | G | T | |
| A/Vietnam/VP-12-03/2012 (1.1) | D | D | G | G | Q | ||
| Escape mutants | N | Y | E | E | E | ||
| Avian strain (clade) | A/whooper swan/Hokkaido/4/2011 (2.3.2.1) | D | N | G | G | N | |
| Conservation rate among human and avian H5N1 (%) | 88.8 | 87.4 | 99.9 | 99.2 | 60.8 | ||
*Amino acids in italic letters are critical changes for OM-b/AY-2C2 or YH-1A1 binding.