Table 3. Validation of Jenkin’s model and Modified Jenkin’s model.

Group*	ANC (×10∧9/L)	ALC (×10∧9/L)	AMC (×10∧9/L)	Total No.	FN in the 1st cycle		P†
					No.	%
Jenkin’s model
Group I	>5.2	>2.4	n/a	155	15	9.7	NS
Group II	≦5.2	≦2.4	n/a	93	9	9.7
Group III	≦4.4	≦2.1	n/a	72	14	19.4
Group IV	≦3.8	≦1.8	n/a	69	13	18.8
Group V (High-risk subgroup)	≦3.1	≦1.5	n/a	39	4	10.3
Model-A
Low-risk subgroup (Group I & II)	>4.4	>2.1	n/a	248	24	9.7	<0.05
High-risk subgroup (Group III,IV & V)	≦4.4	≦2.1	n/a	180	31	17.2
Model-B
Low-risk subgroup (Group I,II & III)	>3.8	>1.8	n/a	320	38	11.9	NS
High-risk subgroup(Group IV & V)	≦3.8	≦1.8	n/a	108	17	15.7
Model-C
Low-risk subgroup	Not fulfill the criteria of high-risk group			337	34	10.1	<0.01
High-risk subgroup	≦4.4	≦2.1	≦0.28	91	21	23.1

*In Jenkin’s model, patients were classified into different groups without overlaps. For example, group IV comprises patients with ANC ≦3.8 and ALC ≦1.8 who do not fulfil the criteria for group V.

^†Chi-square test was used.