Table 2. Pro- and anti-inflammatory cytokine production by RST1 and RST3 B. burgdorferi clinical isolates.

	Cytokine (pg/mL)
Genotype	IL-1β	IL-6	IL-8	IL-10	IL-12p70	TNF-α
RST1 * (n = 4)	24841±7187	79738±17430	73678±21296	9468±1876	3441±3243	45748±21388
RST3 (n = 6)	21898±8148	71340±10956	69671±10190	9807±2641	2392±2728	43941±18476
P value	0.317	0.479	0.826	0.788	0.137	0.981

*B31-4 and A3-M9 lp36− were not included in the RST1 group when calculating averages and performing statistical analysis. Statistical significance was determined using a non-parametric Mann-Whitney U-test. Data shown are from three independent donors assessed in separate experiments.