Figure 5. LysPG formation does not play a role in L. monocytogenes EGD-e resistance to the defensins RC-1 and HNP-1. No significant difference is observed in the percent proliferation of the ΔlysPGS strain (blue) in comparison to the wt strain (red) when incubated for 15 min in the presence of varying concentrations of RC-1 or HNP-1. Data was normalized to bacterial counts resulting from the incubation of both strains in DMEM alone, which was set to 100% proliferation. Calculated P values for the tested concentrations of RC-1 and HNP-1 are not less than 0.05, indicating no statistically significant difference between the percent proliferation of the two strains incubated in these conditions.