Table 2. Spearman correlation between DMR methylation and imprinted gene expression.
| DMR Methylation | Gene expression | rho | P | n |
|---|---|---|---|---|
| 7q21 DMR1 | SGCE | - 0.491 | 0.001 | 46 |
| PEG10 | - 0.423 | 0.003 | 46 | |
| PPP1R9A | 0.559 | 0.000 | 46 | |
| 7q21 DMR1 CpG4 | PON2 | 0.356 | 0.015 | 46 |
| 7q21 DMR1 CpG6 | PON2 | 0.330 | 0.025 | 46 |
| 7q21 DMR2 CpG3 | PEG10 | - 0.292 | 0.047 | 47 |
| PPP1R9A | 0.427 | 0.003 | 47 | |
| 7q21 DMR2 CpG4 | PPP1R9A | 0.328 | 0.024 | 47 |
| 7q21 DMR2 CpG5 | PPP1R9A | 0.368 | 0.011 | 47 |
| ZAC1 DMR CpG6 | ZAC1 | - 0.328 | 0.030 | 44 |
| NDN DMR CpG7 | NDN | - 0.314 | 0.032 | 47 |
| MEG3 DMR CpG2 | MEG3 | 0.535 | 0.000 | 47 |
| CDKN1C promoter | CDKN1C | - 0.310 | 0.034 | 47 |
| CDKN1C promoter CpG4 | IGF2 | - 0.357 | 0.014 | 47 |
| LIT1 | - 0.293 | 0.046 | 47 | |
| H19 DMR CpG4 | IGF2 | - 0.294 | 0.050 | 45 |
| H19 DMR CpG7 | IGF2 | - 0.308 | 0.040 | 45 |
Spearman correlation coefficient (rho) was used to evaluate the correlation between the DNA methylation of each individual CpG position or the mean of all CpG positions in the assesed DMRs with the expression of the local imprinted genes in prostate cancer tissues. Only significant correlations are included in the table (*P < 0.05; **P < 0.01). In the cases where the mean methylation of all CpGs correlated significantly with gene expression, it also did for most of the single CpG positions in that region and is therefore not explicitly shown.