Table 3. Overall association between maternal log10 water arsenic concentration and omnibus EWAS p-values with and without adjusting for 6 imputed leukocyte cell mixture coefficients.
Unadjusted for Leukocyte1 | Adjusted for Leukocyte2 | ||||
---|---|---|---|---|---|
# CpGs | Mean F | Max F | Mean F | Max F | |
All autosomal CpGs (II.a, II.b) |
473929 | 0.002 | 0.002 | 0.065 | 0.015 |
Autosomal CpGs without polymorphisms (II.c, II.d) | 384474 | 0.002 | < 0.001 | 0.059 | 0.013 |
1 Estimated following statistical method described in IIa and IIc. 2Estimated following statistical method described in IIb and IId.