Figure 4. (A) The total outpatient antibacterial use in 20 European countries from 1999 to 2008 (cumulative annual average). DDD, defined daily dose. Data obtained from the ESAC (European Surveillance of Antimicrobial Consumption) project (now ESAC-Net) (http://www.ecdc.europa.eu/en/activities/surveillance/ESAC-Net/). (B) The estimated total consumption (kg active compound) of prescribed antimicrobials for production animals from 2000 to 2008 in Denmark. Data obtained from DANMAP 2008 (http://www.danmap.org/).