Table 2.
Endpoints at 12 months
| Endpoints | LCD group (n=36) | Control group (n=36) | P-value |
|---|---|---|---|
| Plasma glucose at 2 hours after oral glucose load, mg/dL | 127.8±27.1 | 172.6±25.9 | <0.001 |
| Normalization rate of IGT, number (%) | 25 (69.4) | 3 (8.3) | <0.001 |
| Incidence rate of diabetes, number (%) | 0 (0) | 5 (13.9) | 0.02 |
| Fasting plasma glucose, mg/dL | 99.1±8.3 | 110.2±12.7 | <0.001 |
| HbA1c, % | 5.6±0.4 | 6.4±0.5 | <0.001 |
| Body weight, kg | 61.6±9.6 | 68.5±5.9 | <0.001 |
| Fasting plasma insulin, μU/mL | 6.0±4.2 | 9.6±2.9 | <0.001 |
| HOMA-IR | 1.5±1.0 | 2.6±1.0 | <0.001 |
| Serum LDL cholesterol, mg/dL | 125.4±33.3 | 133.1±23.7 | 0.26 |
| Serum HDL cholesterol, mg/dL | 63.3±16.2 | 50.3±10.1 | <0.001 |
| Serum TGs, mg/dL | 97.4±57.9 | 150.6±30.5 | <0.001 |
Abbreviations: HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; IGT, impaired glucose tolerance; LCD, low-carbohydrate diet; LDL, low-density lipoprotein; TGs, triglycerides.