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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Metab Brain Dis. 2013 Dec 19;29(4):1027–1039. doi: 10.1007/s11011-013-9469-0

Table 2.

Clinical and demographic comparisons

Parameter [±S.D.] pHEs [n = 4] Cirrhotic HE [n = 5] Alcoholics [n = 4] Controls [n = 4]
Mean age (years) 55 [7.5] 57 [11.6] 53 [7.5] 59 [11.6]
Gender (M/F) 3/1 2/3 3/1 3/1
Mean PMI 22 [5.6] 34 [19.9] 24 [6.6] 20 [9.5]
Mean brain weight (g) 1287 [86] 1269 [124] 1392 [52] 1372 [135]
Mean brain pH 6.36 [0.20] 6.44 [0.37] 6.70 [0.23] 6.61 [0.23]
Mean Fixation period (months) 84.5 [53.8]* 56.8 [20.9] 15.7 [9.5]* 17.8 [22.5]*
Severity of liver pathology (0,1,2,3)B 0,0,0,4 0,0,0,5 1,1,2,0 1,2,0,0A
Mean daily alcohol consumption (g/day)C,D 211 [114.8] 206 [87.4] 183 [41.0] 5 [6.2]*
Smoking (Ever/Never)C 3/1 3/2 3/1 1/2A
Smoking (Mean pack years)C 25.3 [22.1]A 26.7 [25.1] 27.5 [22.2] 1.9 [2.8]A
*

significant difference, p-value < 0.05

A

Data missing

B

liver pathology: 0 = nil or congestion, 1 = mild steatosis, 2 = severe steatosis/mild fibrosis; 3 = cirrhosis or severe inflammation

C

estimated from medical history and next of kin questionnaires.

D

calculated by mean daily consumption × 365 × years drinking [excluding periods of abstinence].