Figure 5. Histopathology of Af293 and Af5517 infection.

Neutropenic BALB/c mice were infected with Af293 or Af5517 and sacrificed after 3 days for lung histological analysis. (A) Hematoxylin and Eosin (H&E)-stained sections (left panels) depict lung inflammation in mice infected with 5×10⁶ conidia. Adjacent Gomori’s Methanamine Silver (GMS)-stained sections (right panels) show areas of fungal growth. The black bar (bottom right panel) is equivalent to 100 µm. (B) GMS staining representing fungal growth was quantified in sections from mice infected with 2×10⁶ or 5×10⁶ conidia, with the mean of four representative fields displayed for each sample. *p<0.05.