Figure 2. Clonogenic survival of EMT6.5, 4T1.2 and NMuMG cells following conventional/synchrotron broadbeam and MRT irradiations.
(A) EMT6.5 tumour, (B) 4T1.2 tumour and (C) NMuMG normal mouse mammary epithelial cells. BB doses were chosen to match the MRT valley dose, based on Monte Carlo computer simulations. Clonogenic survival for 150/50 µm<175/25 µm<BB. 7.5 Gy Synchrotron BB significantly reduced clonogenic survival compared to 7.5 Gy conventional BB (p<0.0001). Data are represented as mean ± SEM (n = 3).