Table 4. Univariate association of EPIC diagnostic codes (ICD-9 codes) with Cthrc1 for MMC inpatient data, summarized at the major grouping (before the decimal point).

ICD-9	Diagnosis	With Diagnosis	Mean without Diagnosis	Mean with Diagnosis	Test Statistic	p-value	FDR
998	wound infection after surgery	6	13.54	64.09	1560.50	0.0021	0.2788
112	yeast infection	16	16.20	25.89	2918.50	0.0092	0.5470
v70	healthcare maintenance	39	14.61	24.86	5189.00	0.0226	0.5470
285	anemia	81	12.56	17.76	9878.50	0.0280	0.5470
327	obstructive sleep apnea	20	14.43	33.41	3052.00	0.0296	0.5470
599	urinary tract infection	26	13.16	55.53	3735.00	0.0320	0.5470
8	clostridium difficile colitis	7	10.34	41.99	1297.00	0.0373	0.5470
707	ulcer	19	12.04	53.32	3350.00	0.0416	0.5470
v22	pregnant state	10	14.66	38.09	1823.00	0.0421	0.5470
799	hypoxia	17	15.34	37.08	2330.50	0.0498	0.5530

A Wilcoxon rank sum test is used to compare the rank of Cthrc1 levels for patients with and without a given ICD-9 code. Only codes with at least 5 patient instances are included in the analysis. Included results are the mean in each group, the Wilcoxon test statistic, the p-value, and the adjusted p-value (the estimated false discovery rate). Results presented have a p-value <0.05 and the estimated FDR is shown. ICD-9 major codes and a representative diagnosis are shown.