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. 2014 Jun 19;9(6):e100631. doi: 10.1371/journal.pone.0100631

Figure 4. Gender dimorphism of cardiac dysfunction was blunted in response to high dose of LPS (9 mg/kg)/PepG (1 mg/kg) co-administration.

Figure 4

Panel A–D: Male or female mice received either LPS (9 mg/kg)/PepG (1 mg/kg) or PBS intraperitoneally. Cardiac function was assessed at 18 hours. (A) Representative M-mode echocardiograms; percentage (%) (B) ejection fraction (EF); (C) fractional shortening (FS); and (D) fractional area of change (FAC). The following groups were studied: Male+vehicle (n = 5); Female+vehicle (n = 4); Male+LPS/PepG (n = 11); Female+LPS/PepG (n = 6). Data are expressed as means ± SEM for n number of observations. ★P<0.05 versus the respective sham group, #P<0.05 versus male LPS/PepG group.