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. 2014 Apr 4;139(2):271–283. doi: 10.1093/toxsci/kfu061

TABLE 2. Potential Health Effects of Air Pollutants Associated with Shale Gas Development.

Pollutant Potential health effects
Methane • Explosion and fire
• Asphyxiation in confined space
• Global climate change
Nonmethane volatile organic compounds including BTEXa • Ozone precursors
• Leukemia and other hematological effects (benzene, formaldehyde)
• Upper respiratory tract inflammation
• Central nervous system effects in confined spaces
Oxides of nitrogen • Ozone precursors
• Asthma and other acute respiratory effects
Ozone including photochemical oxidants • Asthma and other acute respiratory effects
• Loss of lung function
• Premature mortality
Particulates including diesel exhaust • Asthma and other acute and chronic respiratory effects
• Premature mortality
• Cancer
Silica dust • Chronic lung disease (silicosis; particularly among workers)

aBTEX: benzene, toluene, ethyl benzene, and xylenes.