Table 3.

Health benefits and costs for metformin and the combination of metformin with nateglinide

	Metformin	Combination	Difference
Cumulative cost (mean per patient)
Complications	£3,548	£3,084	£-464
Total	£5,093	£7,159	£2,066
Survival (mean, years)
Life years (discounted)	13.5 (11.7)	13.9 (12.1)	0.39 (0.32)
Quality Adjusted (discounted)	12.2 (10.7)	12.6 (11.0)	0.46 (0.37)
Cost-effectiveness
Cost per LYG (discounted LYG)			£5,403 (6,772)
Cost per QALY (discounted QALY)			£4,500 (5,609)

LYG = Life Year Gained QALY = Quality Adjusted Life Year