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Periodic and spontaneous seizures. A: experimentally observed spontaneous periodic seizures in the CA1 region at 8.5 mM potassium in the perfusate [reproduced with permission from Traynelis and Dingledine 1988]. B: in the model, membrane potential and local extracellular potassium concentration, [K+]o, shows periodic seizures occur with similarly elevated 8.5 mM bath potassium.
