Table 1. RBPs—features and function.
| RBP | Band# | Function | RBD | RBD# | Known binding sequence | Presence in MICB 3′UTR |
|---|---|---|---|---|---|---|
| FUBP3 | 4 | Transcription and translation | KH | 4 | UG-repeats | No |
| HuR | 8 | Splicing and mRNA stability | RRM | 3 | AU-rich | Yes |
| XRN2 | 1 | Degradation and premature transcription termination | CCHC-type zinc-finger | 1 | - | - |
| MATR3 | 1 | Trafficking and mRNA stability | RRM | 2 | WWCUUD | Yes |
| CUGBP1 | 5 | Splicing, translation and mRNA stability | RRM | 3 | GU-rich | Yes |
| IGF2BP2 | 4 | Trafficking and translation | RRM | 1/2 | CAUH or MAWWMA | Yes |
| KH | 4 | |||||
| hnRNP-M | 2 | mRNA processing | RRM | 3 | Poly(G) and poly(U) | No |
KH, hnRNP-K-homology domain; mRNA, messenger RNA; RRM, RNA-recognition motif; UTR, untranslated region.
The top ranking RBPs and their features and known functions are listed. Binding site nucleotide codes: M=C/A; W=A/U; D=U/A/G; H=C/A/U.