Table 1.
Fatty acid composition of the phosphatidylcholine fraction within mammary glands adjacent to tumours
Mammary gland PC fatty acids |
Diet |
||
---|---|---|---|
0% | 3% | 9% | |
LA (18:2n-6) |
30.8 ± 2.1a |
20.9 ± 2.3b |
11.9 ± 1.6c |
AA (20:4n-6) |
8.3 ± 0.5a |
3.8 ± 0.2b |
7.9 ± 2.1ab |
DPA (22:5n-6) |
0.8 ± 0.1a |
traceb |
traceb |
ALA (18:3n-3) |
tracea |
tracea |
tracea |
EPA (20:5n-3) |
tracea |
0.7 ± 0.1b |
4.0 ± 0.8c |
DPA (22:5n-3) |
tracea |
0.3 ± 0.4ab |
1.9 ± 0.9b |
DHA (22:6n-3) |
tracea |
tracea |
tracea |
Total n-6 |
41.4 ± 1.7a |
25.2 ± 2.1b |
20.3 ± 1.2c |
Total n-3 |
0.03 ± 0.03a |
1.1 ± 0.5b |
6.0 ± 1.5c |
n-6/n-3 ratio |
1292.3a |
23.8 ± 8.5b |
3.4 ± 1.0c |
Total SFA |
43.6 ± 1.1a |
45.9 ± 0.4ab |
52.6 ± 0.9b |
Total MUFA |
14.1 ± 1.7a |
23.4 ± 2.0a |
21.0 ± 1.9b |
Total PUFA |
41.7 ± 1.3a |
26.4 ± 2.6b |
26.4 ± 1.4c |
P/S Ratio | 1.0 ± 0.1a | 0.6 ± 0.04b | 0.5 ± 0.05c |
n = 4 for the 3% n-3 PUFA diet, n = 5 for both the 0% n-3 and 9% n-3 PUFA dietary interventions. Values in the same row not sharing the same superscript are significantly different from one another as determined by a one-way ANOVA (p < 0.05).