Figure 5.

Leakage data for magainin 2 (open squares), C₁₂EO₈ (open circles), and mixtures thereof (solid symbols) acting on 30 μM POPC/POPG (1:1 mol/mol) vesicles. (A) Dye efflux after 1 h, E, as a function of the concentration of magainin (for pure magainin and mixtures) or C₁₂EO₈. (Solid symbols) Mixtures of constant C₁₂EO₈ of 45 μM (diamonds and down-triangles for two independent batches). (Solid line) Value calculated using Eq. 3, assuming additive action (CI = 1) (dotted lines are to guide the eye only). Concerted action is additive, within error. (B) E as a function of the fluorescence lifetime of entrapped dye, τ_E, on a reciprocal scale. To see this figure in color, go online.