Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cancer cells with PIKE-A amplification resist to apoptosis. (A) Apoptotic assay. Various human cancers were treated with 250 nM staurosporine for 16 h, and followed by chromatin condensation and fragmentation analysis with DAPI staining. PIKE-A amplified cells display lower apoptotic activity compared to cells with normal copy. (B) Western blotting analysis of Lamin A/C and Caspase-3 cleavage during apoptosis.
