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. 2004 Apr 26;101(18):7022–7027. doi: 10.1073/pnas.0401025101

Fig. 2.

Fig. 2.

Dc mutant embryos have ectopic Tbx10 mRNA expression. In situ hybridization analysis revealed widespread ectopic overexpression of Tbx10 at E9.5 (B and C) and E10.5 (F and G)in Dc mutants compared with the wild-type (A and E) littermates. Because of the short detection time used due to overexpression of Tbx10 in mutant embryos, the restricted wild-type Tbx10 expression pattern in the developing hindbrain is barely visible. (D and H) The pattern of p23 mRNA expression in wild-type embryos is very similar to that of the ectopic Tbx10 expression in Dc mutant embryos.