Table 1.
Demographics and clinicopathological characteristics of 48 patients
Characteristics | na | % |
---|---|---|
Age | ||
Median, range (years) | 58, 43–82 | |
Gender | ||
Male | 37 | 77.1 |
female | 11 | 22.9 |
Smoking history (pack years)b | ||
Never | 15 | 31.3 |
1–20 | 6 | 12.5 |
21–40 | 10 | 20.8 |
41–60 | 9 | 18.8 |
>60 | 8 | 16.7 |
Karnofsky performance status | ||
60 | 2 | 4.2 |
70 | 7 | 14.6 |
80 | 23 | 47.9 |
90 | 16 | 33.9 |
Disease stage | ||
IIIa | 20 | 41.7 |
IIIb | 28 | 58.3 |
Tumour histology | ||
Squamous cell carcinoma | 31 | 64.6 |
Adenocarcinoma | 10 | 20.8 |
Not specified | 7 | 14.6 |
Tumour location | ||
Left upper lobe | 12 | 25.0 |
Left lower lobe | 7 | 14.6 |
Right upper lobe | 14 | 29.2 |
Right mid-lobe | 5 | 10.4 |
Right lower lobe | 10 | 20.8 |
Tumour location | ||
Peripheral | 16 | 33.3 |
Central | 32 | 66.7 |
Treatment choice | ||
RT alone | 3 | 6.3 |
RT + adjuvant chemotherapy | 1 | 2.1 |
Concurrent chemoradiotherapy alone | 0 | 0.0 |
Concurrent + adjuvant chemotherapy | 5 | 10.4 |
Induction chemotherapy + RT | 9 | 18.8 |
Induction + RT + adjuvant chemotherapy | 11 | 22.9 |
Induction + concurrent chemotherapy | 12 | 25.0 |
Induction + concurrent + adjuvant chemotherapy | 7 | 14.6 |
Target volume median, range (cm3) | ||
PTV | 438.3, 204.9–1116.2 | |
PTVG | 131.0, 10.9–509.2 | |
Treatment dose median, range (Gy) | ||
PTV | 51.58, 45.0–63.0 | |
PTVG | 63.0, 55.0–74.2 | |
PTVG dose (Gy) | ||
55–59 | 8 | 16.7 |
60–64 | 20 | 41.7 |
65–69 | 16 | 33.3 |
≥70 | 4 | 8.3 |
PTV, planning target volume; PTVG, gross tumour volume; RT, radiation therapy.
n denotes the number of patients, unless otherwise indicated.
1 pack year = smoking 20 cigarettes per day for 1 year.