Table 1.
Influence of Serum on Gene Expression in Primary and Immortalized Human Meibomian Gland Epithelial Cells
|
Group |
Genes ↑ |
Genes ↓ |
Total Genes |
| Undiff vs. serum | |||
| Primary | 2125 | 2358 | 4483 |
| Immortalized | 2025 | 2787 | 4812 |
| SFM vs. serum | |||
| Primary | 1368 | 1814 | 3182 |
| Immortalized | 1602 | 1187 | 2789 |
Data were evaluated without log transformation. The expression of listed genes was significantly (P < 0.05) up- (↑) or (↓) downregulated by serum exposure, compared to the undifferentiated (“Undiff”) or SFM control groups.