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. 2014 Jun 20;8:170. doi: 10.3389/fncel.2014.00170

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Copyright © 2014 Phillips, Baktir, Srivatsan and Salehi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relationship between the total volume of the hippocampus and age in met and non-met carriers. Using a polynomial fitting curve, we found a significant correlation (r = −0.447, P = 0.0150) between age and the volume of the hippocampus in met carriers. No such correlation was found in non-met carriers (r = −0.178, P = 0.2639). Furthermore, the slope of the regression in the hippocampal volume of met carriers (slope = −0.038) was twice the value of the slope of regression in non-met carriers (slope = −0.016; Published from Sanchez et al., 2011).