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Mean fluorescence intensity of doxorubicin after subcellular fractionation of nuclei and cytosol compartments of PANC-1 cells after exposure to free doxorubicin, unmodified Lipodox and Lipodox targeted with either phage protein EPSQSWSM or ETPPSWGG at a constant doxorubicin concentration of 35 µg/ml for 4 h.
| Mean intensity fluorescence (%) | Nucleus | Cytoplasm |
|---|---|---|
| Lipodox | 58.38 | 41.52 |
| EPSQSWSM-Lipodox | 81.12 | 18.88 |
| ETPPSWGG-Lipodox | 83.37 | 16.63 |
| Doxorubicin | 82.72 | 17.28 |
