Table II.
Mean fluorescence intensity of doxorubicin after subcellular fractionation of nuclei and cytosol compartments of PANC-1 cells after exposure to free doxorubicin, unmodified Lipodox and Lipodox targeted with either phage protein EPSQSWSM or ETPPSWGG at a constant doxorubicin concentration of 35 µg/ml for 4 h.
Mean intensity fluorescence (%) | Nucleus | Cytoplasm |
---|---|---|
Lipodox | 58.38 | 41.52 |
EPSQSWSM-Lipodox | 81.12 | 18.88 |
ETPPSWGG-Lipodox | 83.37 | 16.63 |
Doxorubicin | 82.72 | 17.28 |