Table 1.
Dual-AAV Constructs Used in the Study
Name | Description | Reference |
---|---|---|
YZ27 | The upstream vector of the R20 overlapping dual-vector set. It contains the CMV promoter, 5′ half of the GFP-fused mini-dystrophin gene (till the end of R20). | Zhang and Duan (2012) and Zhang et al. (2013) |
YZ22 | The downstream vector of the R20 overlapping dual-vector set. It contains the 3′ half of the GFP-fused mini-dystrophin gene (starting from R20) and the pA signal. | Zhang and Duan (2012) and Zhang et al. (2013) |
WL40 | The upstream vector of the R7 overlapping dual-vector set. It is similar to YZ27 except that the R20 is replaced by R7. | Fig. 1 (this study) |
WL43 | The downstream vector of the R7 overlapping dual-vector set. It is similar to YZ22 except that the R20 is replaced by R7. | Fig. 1 (this study) |
WL41 | The upstream vector of the R8 overlapping dual-vector set. It is similar to YZ27 except that the R20 is replaced by R8. | Fig. 1 (this study) |
WL44 | The downstream vector of the R8 overlapping dual-vector set. It is similar to YZ22 except that the R20 is replaced by R8. | Fig. 1 (this study) |
WL42 | The upstream vector of the R9 overlapping dual-vector set. It is similar to YZ27 except that the R20 is replaced by R9. | Fig. 1 (this study) |
WL45 | The downstream vector of the R9 overlapping dual-vector set. It is similar to YZ22 except that the R20 is replaced by R9. | Fig. 1 (this study) |
AAV, adeno-associated virus; CMV, cytomegalovirus.
All vectors are flanked by AAV inverted terminal repeat.