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. 2014 Feb 28;25(6):552–562. doi: 10.1089/hum.2013.210

Table 2.

Tri-AAV Constructs Used in the Study

Name Description Reference
WL30 The head vector of the tri-AAV vector set. It contains the CMV promoter, human dystrophin exons 1–26, a splicing donor from Ad41E1a intron, and the highly recombinogenic AP1 sequence. Figs. 2A, 2B, and 3A (this study)
WL34 The body vector of the hybrid-overlapping (HO) tri-AAV vector set. It contains the AP1 sequence, a splicing acceptor from Ad41E1A intron, human dystrophin exon 27 to the middle of exon 53). Fig. 2A (this study)
WL37 The tail vector of the HO tri-AAV vector set. It contains exons 50–79, and the pA signal. Fig. 2A (this study)
WL33 The body vector of the hybrid–hybrid (HH) tri-AAV vector set. It contains the AP1 sequence, a splicing acceptor from Ad41E1A intron, human dystrophin exons 27–48, a synthetic splicing donor from pCI intron, and the highly recombinogenic AP2 sequence. Figs. 2B and 3A (this study)
WL35 The tail vector of the HH tri-AAV vector set. It contains the AP2 sequence, a synthetic splicing acceptor from pCI intron, human dystrophin exons 49–79, and the pA signal. Fig. 2B (this study)
WL38 The tail vector of the flagged HH tri-AAV vector set. It is identical to WL35 except for a flag tag fused at the C-terminal end. Fig. 3A (this study)

The constructs are listed in the order they appear in the figures. All vectors are flanked by AAV inverted terminal repeat.

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