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. 2014 Feb 25;25(6):529–538. doi: 10.1089/hum.2013.111

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Copyright 2014, Mary Ann Liebert, Inc.

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FIG. 3. — The MCM enzyme activity in liver extracts. Hepatic enzyme activity from normal mice (n=6, ), Mut^−/−MUT^h2 untreated mice (n=6, ), and HIV-1SDmEF1αmurSigHutMCM-treated mice (n=5, ). The HIV-1SDmEF1αmurSigHutMCM-treated mice had a mean±SEM of 66±21 (nM/min/μg of total hepatocyte protein) and is significantly different (p<0.05) compared with the Mut^−/−MUT^h2 untreated group (undetectable). The error bars represent SEM. The * and α indicate significant difference between the treatment groups (normal vs. untreated) and (treated vs. untreated), respectively. The p-value between groups was calculated using one-way ANOVA with Tukey's post hoc test.

Inline graphic — The MCM enzyme activity in liver extracts. Hepatic enzyme activity from normal mice (n=6, ), Mut^−/−MUT^h2 untreated mice (n=6, ), and HIV-1SDmEF1αmurSigHutMCM-treated mice (n=5, ). The HIV-1SDmEF1αmurSigHutMCM-treated mice had a mean±SEM of 66±21 (nM/min/μg of total hepatocyte protein) and is significantly different (p<0.05) compared with the Mut^−/−MUT^h2 untreated group (undetectable). The error bars represent SEM. The * and α indicate significant difference between the treatment groups (normal vs. untreated) and (treated vs. untreated), respectively. The p-value between groups was calculated using one-way ANOVA with Tukey's post hoc test.