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. 2014 Feb 25;25(6):529–538. doi: 10.1089/hum.2013.111

FIG. 6.

FIG. 6.

The comparison of hepatic MMA concentrations between treatment groups. Average hepatic MMA concentrations of normal mice (n=6, Inline graphic), Mut−/−MUTh2 untreated mice (n=6, Inline graphic), and HIV-1SDmEF1αmurSigHutMCM-treated mice (n=5, Inline graphic) are shown. The mean±SEM concentrations of hepatic MMA for normal mice, Mut−/−MUTh2 untreated group, and HIV-1SDmEF1αmurSigHutMCM-treated mice are 7±1 μM/g tissue, 1003±124 μM/g tissue, and 133±20 μM/g tissue, respectively. Statistical analysis demonstrated a significant difference between the untreated and normal group. Also, the analysis demonstrated a significant reduction (p<0.05) of hepatic MMA concentration in HIV-1SDmEF1αmurSigHutMCM-treated mice compared with the untreated group. However, the analysis showed no significant difference between the HIV-1SDmEF1αmurSigHutMCM-treated group and the normal group. The error bars represent SEM; * and α indicate a significant difference between treatment groups, (normal vs. untreated) and (untreated vs. treated), respectively. The p-value among the groups was calculated using one-way ANOVA with Tukey's post hoc test.