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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Leuk Lymphoma. 2013 Jun 12;55(2):358–364. doi: 10.3109/10428194.2013.800200

Table 3.

Multivariable models for four major outcomes

Overall Survival Disease Free Survival Relapse Non-relapse mortality

Factor Hazard
Ratio
Lower
95% CL
Upper
95% CL
P Hazard
Ratio
Lower
95% CL
Upper
95% CL
P Hazard
Ratio
Lower
95% CL
Upper
95% CL
P Hazard
Ratio
Lower
95% CL
Upper
95% CL
P
Race match
Matched 1.0 1.0 1.0 1.0
Mismatched 1.0 0.7 1.3 .86 0.9 0.6 1.4 .77 0.8 0.4 1.5 .48 1.1 0.7 1.8 .68

Recipient race
Caucasian 1.0 1.0 1.0 1.0
Ethnic minority 1.0 0.7 1.5 .84 1.1 0.7 1.7 .74 1.6 0.8 3.3 .23 0.8 0.4 1.5 .51

Donor & HLA match
URD well matched 1.0 1.0 1.0 1.0
URD partially matched 1.5 1.0 2.1 .03 1.4 0.9 2.1 .14 1.0 0.5 2.0 .98 1.3 0.8 2.2 .27
URD mismatched 1.7 1.2 2.4 <.01 1.5 1.0 2.2 .07 0.6 0.3 1.3 .19 1.9 1.1 3.1 .01
UCB 5/6 or 6/6 0.9 0.7 1.2 .50 1.0 0.7 1.4 .82 1.6 0.9 2.6 .12 0.6 0.3 1.0 .03
UCB 4/6 1.1 0.8 1.6 .45 1.1 0.8 1.6 .63 1.6 0.9 2.8 .10 0.7 0.4 1.2 .18

Disease Category
Malignant, high risk 2.4 1.9 3.2 <.01 1.7 1.4 2.2 <.01 2.0 1.4 2.7 <.01 1.1 0.8 1.5 .67
Malignant, standard risk 1.6 1.3 2.1 <.01 1.0 1.0 1.0
Non-malignant 1.0 excluded

CMV
R+ 1.1 0.9 1.4 .21 1.1 0.9 1.3 .50 0.9 0.7 1.2 .49 1.1 0.8 1.6 .41
R- 1.0 1.0 1.0 1.0

Conditioning
Myeloablative 1.0 0.8 1.2 .90 0.8 0.6 1.0 .02 0.6 0.5 0.9 <.01 1.1 0.7 1.6 .75
RIC 1.0 1.0 1.0 1.0

Abbreviations: URD, unrelated donor; UCB, umbilical cord blood; RIC, reduced intensity conditioning