Table 2.
Associations between ovarian cancer outcomes and pre-diagnosis BMI
| Pre-Diagnosis BMI, kg/m2 | ||||
|---|---|---|---|---|
| BMI <18.5 (N=13) |
18.5 ≤BMI<25 (N=217) |
25≤BMI<30 (N=199) |
BMI≥30 (N=171) |
|
| Total Deaths | n=8 | n=131 | n=113 | n=94 |
| Age-Adjusted HR (95% CI) | 1.44 (0.71–2.95) | 1.00 | 0.91 (0.71–1.17) | 1.00 (0.77–1.30) |
| Multivariate Adjusted HR* (95% CI) | 1.14 (0.55–2.40) | 1.00 | 0.77 (0.59–1.01) | 0.95 (0.70–1.29) |
| Ovarian Cancer Deaths | n=6 | n=115 | n=100 | n=80 |
| Age-Adjusted HR (95% CI) | 1.22 (0.54–2.77) | 1.00 | 0.92 (0.70–1.20) | 0.97 (0.73–1.29) |
| Multivariate Adjusted HR* (95% CI) | 0.90 (0.39–2.11) | 1.00 | 0.79 (0.59–1.05) | 0.95 (0.69–1.32) |
Abbreviations: BMI, body mass index; MET, metabolic equivalent task; HR, Hazard Ratio
Multivariate Model adjusted for age, stage, histology, time from study enrollment to ovarian cancer diagnosis, physical activity, hormone therapy use, smoking, history of diabetes and status in calcium and vitamin D trial, diet modification trial, hormone therapy trial and observational study.