The relative change in tumour cellularity for each clinical response category: complete response (CR), partial response (PR), no response (NR), progressive disease (PD). Relative change in tumour cellularity was calculated as follows: (percentage tumour cellularity at resection- percentage tumour cellularity in core needle biopsy)/percentage tumour cellularity in core needle biopsy. The colored rectangle indicates the 25th and 75th percentiles of the distribution; the median is indicated by the white horizontal line within the rectangle From the box plot, a variable, the change in cellularity in more variable in PR, NR and PD groups as compared to CR. This indicates that core needle biopsy specimens may underestimate the overall cellularity in the resection