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. 2014 Jun 20;9(6):e100196. doi: 10.1371/journal.pone.0100196

Table 1. Treatment paradigm for neurite growth/regrowth assessment.

Treatment Groups Treatment from 0 to 24 h Treatment from 24 to 72 h
72 h (C) Control Control
72 h (C+M) Control + Mor Control + Mor
72 h (C+M+N) Control + Mor + Nal Control + Mor + Nal
72 h (H) HIV HIV
72 h (H+M) HIV + Mor HIV + Mor
72 h (H+M+N) HIV + Mor + Nal HIV + Mor + Nal
24 h (H) then 48 h (C) HIV Control
24 h (H+M) them 48 h (C+M) HIV + Mor Control + Mor
24 h (H+M+N) then 48 h (C+M+N) HIV + Mor + Nal Control + Mor + Nal

Control  =  Controlsup; HIV  =  HIV+ sup (p24 = 25 pg/ml); Mor  =  morphine sulfate (500 nM); Nal  =  naloxone (1.5 µM).