Table 2. Clinical descriptive data for patient groups.
Recent-Onset | Chronic | p | ||
N | 16 | 19 | ||
Medication | ||||
Unmedicated | 5 | 2 | ns | |
Typical Antipsychotic | 0 | 7a | * | |
Atypical Antipsychotic | 11 | 13a | ns | |
Antidepressant | 6 | 9 | ns | |
Onset Age | 22.1(4.2) | 24.4(6.5) | * | |
Duration (yrs.) | .8(.92)b | 15.8(7.3)c | *** | |
GAF | ||||
Total | 55.2(10.0) | 53.6(12.0) | ns | |
SAPS | ||||
Delusions | .52(.53) | 1.02(.76) | ns | |
Hallucinations | .67(.85) | .98(1.0) | ns | |
Thought Disorder | .27(.50) | .75(.90) | ** | |
Bizarre Behaviour | .47(.58) | .43(.58) | ns | |
Total | .48(.35) | .86(.61) | ** | |
SANS | ||||
Alogia | 1.21(.89) | .91(1.0) | ns | |
Affective Flattening | 1.51(.81) | 1.71(1.3) | ns | |
Inappropriate Affect | .80(1.0) | 1.21(1.2) | ns | |
Avolition | 2.22(.88) | 2.25(1.2) | ns | |
Anhedonia | 2.09(1.1) | 2.17(1.5) | ns | |
Attention | 1.31(1.5) | 1.35(1.4) | ns | |
Total | 1.63(.75) | 1.67(.87) | ns |
Clinical assessments for patient groups. Medication status and mean (SD) of Age, Duration of Illness, SAPS, SANS and GAF scores. SAPS and SANS scores are scaled to a maximum symptom severity of 5. GAF scores reflect percentage of optimal functioning. Last column contains P values obtained from a t-test or chi-squared analysis, as appropriate, comparing recent-onset to chronic groups.
* p<.05;
** p<.01;
*** p<.001; ns Not Significant.
Three individuals were taking both typical and atypical antipsychotic medication.
Range 0.2 to 2 years.
Range 5 to 29 years.