Table 4. Comparison of CSD Onset Latency across participant groups and cortical regions of interest.
Onset Latency | ||||
Region of Interest | Control | Schizophrenia | Group Difference | |
Heschl's gyrus | 94.0 (2.3) | 95.3 (3.1) | 1.4 (3.9) | |
Planum Temporale | 95.3 (2.3) | 101.2 (2.1) | 5.8 (3.2)† | |
Middle temporal gyrus | 94.5 (3.0) | 105.0 (2.6) | 10.6 (3.9) ** | |
Parietal cortex | 95.0 (2.6) | 100.0 (3.0) | 5.0 (4.0) | |
Frontal cortex | 111.1 (6.7) | 98.5 (15.1)a | a |
The upper portion of this table summarises the onset latency of the CSD within each region of interest for both participant groups. Onset latencies are in milliseconds relative to stimulus onset, which occurs 50 ms before standard and duration deviant stimuli can be differentiated. Values in brackets are the standard error of the mean (SEM) derived from the bootstrap analysis, and not the standard deviation of onset latencies measured from each individual. The right-most column contrasts patient to control data showing the mean difference and the bootstrapped SEM for that comparison. Significance levels were determined using t-tests based upon the bootstrap SEM estimate for that comparison, rather than using a pooled SEM estimate. The lower portion of the table presents the delay in onset latency within each ROI relative to that in Heschl's gyrus. The right-most column contrasts these delays between control and patient groups, and as such measures an interaction between Group and ROI. Excluding the frontal ROI, SEM is relatively consistent across ROIs and participant groups.
Trend at p = .07;
*p<.05;
**p<.01.
Note variance of the onset latency in frontal cortex for the patient group is excessively large. This measure was excluded from all subsequent analysis and interpretation.