Table 2. Overall survival and 60-month survival.

		Overall				60 months
Variable	Value	Total (n)	Events (n)	HR	95% CI	Survival probability	95% CI
Gender	Male (ref)	1022	789	1.00	–	0.54	[0.51−0.57]
	Female	260	197	1.12	[0.96−1.31]	0.48	[0.42–0.54]
Tumor location	Glottic larynx (ref)	425	282	1.00	−	0.71	[0.67−0.75]
	Lip	85	54	0.88	[0.66−1.18]	0.75	[0.67−0.85]
	Oral cavity	261	210	2.04	[1.70−2.44]	0.36	[0.31−0.43]
	Oropharynx	148	129	2.37	[1.92−2.92]	0.37	[0.30−0.46]
	Nasopharynx	39	23	1.35	[0.88−2.06]	0.52	[0.37−0.74]
	Hypopharynx	135	123	2.83	[2.29−3.51]	0.33	[0.26−0.42]
	Supraglottic larynx	189	165	1.70	[1.40−2.06]	0.50	[0.43−0.57]
T-class	T1 (ref)	454	293	1.00	−	0.74	[0.70−0.78]
	T2	354	281	1.63	[1.38−1.92]	0.53	[0.48−0.58]
	T3	200	170	2.26	[1.87−2.73]	0.38	[0.32−0.45]
	T4	274	242	3.18	[2.68−3.78]	0.27	[0.22−0.33]
N-class	N0 (ref)	891	641	1.00	−	0.64	[0.61−0.67]
	N1	138	125	2.10	[1.73−2.54]	0.33	[0.26−0.42]
	N2	174	147	2.45	[2.04−2.94]	0.28	[0.22−0.36]
	N3	79	73	3.82	[2.99−4.89]	0.11	[0.06−0.21]
M-class	M0 (ref)	1266	972	1.00	−	0.53	[0.50−0.56]
	M1	16	14	8.51	[4.97−14.58]	0.00	−
Prior malignancies	No (ref)	1160	880	1.00	−	0.54	[0.51−0.57]
	Yes	122	106	1.62	[1.32−1.98]	0.36	[0.28−0.45]
ACE27	Grade 0 (ref)	782	574	1.00	−	0.57	[0.54−0.61]
	Grade 1	239	176	1.17	[0.99−1.39]	0.52	[0.46−0.59]
	Grade 2	185	164	1.66	[1.40−1.98]	0.44	[0.38−0.52]
	Grade 3	76	72	2.52	[1.97−3.23]	0.25	[0.17−0.37]
Age class	<50 (ref)	173	100	1.00	−	0.66	[0.59−0.74]
	50–59	339	234	1.24	[0.98−1.57]	0.59	[0.54−0.65]
	60–69	404	328	1.73	[1.38−2.16]	0.52	[0.47−0.57]
	> = 70	366	324	2.53	[2.02−3.18]	0.40	[0.36−0.46]
Total		1282	986			0.52	[0.50−0.55]

HR. Hazard ratio.

CI. Confidence interval.