Figure 2.

Illustration of columnar laminar neural activity during a cognitive task. (A) Primate brain with prefrontal cortex (PFC) cortical minicolumn and the layers L2/3 and 5. (B) Behavioural delayed match to sample task with the sequence of events (focus, sample presentation, delay period, match array and the arrows representing target selections in object and spatial trials). (C) Interlaminar display of recording array. (D) Minicolumnar interlaminar processing of target selection during the match phase of the task. Perievent and cross-correlation (post- versus pre-match) histograms depict the functional role in integration/selection of prefrontal cortical layers and minicolumns. Adapted from Opris et al., 2012a.