Table 1. Interactions confidence measured by Class scores used to represent different edge widths in the networks.
Class | Score | Edge width | Parameters1 |
A | +9 | 2.5 | Experimental/PubMed ID >1 (at least one not HT)/same CC |
B | +7/+8 | 2.0 | Experimental/PubMed ID >1 or Experimental/PubMed ID >1/same CC |
C | +6 | 1.5 | Experimental/PubMed ID = 1/same CC |
D | +5 | 1.0 | Experimental/PubMed ID = 1 |
E | +4 | 0.5 | Experimental/PubMed ID = 0 |
Parameters used to calculate the Class scores: interaction described as experimental (not predicted) (+4); interaction described in more than one paper (PubMed ID >1) and at least one paper not describing high-throughput (HT) experiments (+4); interaction described in more than one paper (PubMed ID >1) (+3); interaction described in only one paper (PubMed ID = 1) (+1); interacting nodes described in the same cellular component (CC) (+1). For novel interactions not described in any paper (PubMed ID = 0), even if the interacting nodes are described in the same CC, it will be assigned Class score E.