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. 2013 Dec 28;82(2):233–245. doi: 10.3797/scipharm.1310-23

Tab. 1.

Binding constant of TFZ to HSA containing LCFA at several LCFA/HSA molar ratios.

LCFA/HSA (−) aK×10−4 (M−1)

CPA LRA OLA LNA
0 2.33±0.14 2.33±0.14 2.33±0.14 2.33±0.14
1 1.79±0.03 2.66±0.22 2.50±0.16 2.71±0.17
2 1.76±0.06 3.06±0.12 2.61±0.25 3.11±0.03
3 1.56±0.13 3.33±0.20 2.90±0.08 3.41±0.05
4 1.65±0.14 3.65±0.11 2.70±0.06 3.02±0.08
5 1.48±0.16 3.57±0.05 2.53±0.11 2.65±0.21
6 1.73±0.15 3.26±0.27 0.97±0.06 1.94±0.13
7 1.56±0.09 3.03±0.25 0.96±0.06 1.10±0.04
a

mean ± standard deviation (n = 3).