Tab. 5.
Evaluation of core tablets
| Formulation | Hardness (kg/cm2) | Friability (%) | %Drug content | Disintegration time (sec.) |
|---|---|---|---|---|
| S1 | 3.6±0.17 | 0.61±0.10 | 98.99±0.3 | 67.4±1.2 |
| S2 | 3.7±0.11 | 0.67±0.11 | 99.29±0.7 | 38.5±1.8 |
| S3 | 3.3±0.15 | 0.65±0.11 | 99.45±0.11 | 42.1±1.3 |
| S4 | 3.8±0.11 | 0.63±0.15 | 99.75±0.15 | 30.2±1.5 |
| S5 | 3.5±0.12 | 0.62±0.09 | 99.89±0.12 | 14.4±1 |
| S6 | 3.2±0.10 | 0.60±0.16 | 99.25±0.13 | 71.2±1.5 |
| S7 | 3.9±0.08 | 0.62±0.13 | 99.76±0.11 | 69.3±1.7 |
| S8 | 3.5±0.16 | 0.62±0.16 | 99.69±0.10 | 52.8±1.2 |
| S9 | 3.6±0.15 | 0.63±0.11 | 99.88±0.09 | 48.6±1.4 |
| S10 | 3.8±0.14 | 0.62±0.12 | 99.92±0.11 | 38.7±1.3 |