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. 2014 Feb 19;23(14):3641–3656. doi: 10.1093/hmg/ddu073

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© The Author 2014. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Basal expression levels of the major HSPs in young and old mice. (A) qPCR analysis of basal expression levels of Hspa1a/b, Hspb1 and Dnajb1 in brain regions and peripheral tissues from mice at 22 months of age when compared with 3 months (n = 8/age). (B) Relative basal levels of HSPs in brain regions and peripheral tissues of mice at 22 months of age when compared with 3 months (n = 7/age). (C) Representative western blots used for the quantification in (B). Data are the mean ± SEM. *P < 0.05; **P < 0.01. Asterisk indicates the statistically significant difference in the level of induction. Muscle, quadriceps; L.C., loading control; mth, months.